Post-Doctoral Research Fellow – T cell Immunity and Cancer Immunotherapy

Seattle Children’s Research Institute and The University of Washington School of Medicine
Seattle, WA

Laboratory of Dr. Surojit Sarkar is seeking highly motivated post-doctoral fellows to join his energetic and productive research group. The Sarkar Lab is pursuing fundamental research on the mechanisms underlying T cell immunity to acute and chronic pathogens, and cancer. The research program currently lies at the translational interface of immunology aimed at elucidating the mechanistic basis of immunological memory and T cell exhaustion, functional engineering of CAR T cells and discovery of novel immunotherapies to cancer. Located in the heart of the world-class biomedical research cluster in Seattle, the Sarkar laboratory has existing collaborations and synergies with Fred Hutchinson Cancer Research Center, Benaroya Research Institute and Institute for Systems Biology. Interested candidates are encouraged to directly send an email to Dr. Sarkar with their detailed CV and a list of references.

For more information on past publications and the research program, please see:

Google Scholar

Essential requirements: The position requires independent, career-focused and creative individuals well versed in the field of T cell immunology in animal models. The applicant must be well trained to immediately take on impactful fundamental and translation immunology projects in the lab.

• PhD or MD/PhD in Immunology or other closely related field with at least one published first-authored peer-reviewed manuscript from graduate research work.
• New doctoral graduate or post-graduate experience of 0-3 years working on a T cell immunology related project.
• Expertise in fundamental T cell immunology concepts and experimentation.
• Experience working with mouse colony, in vivo murine experimentation and techniques.
• Expertise with core cellular immunology techniques including multi-color flow cytometry, in vitro T cell stimulation assays, and mammalian cell culture.
• Proficiency with molecular techniques such as DNA/RNA isolation, cloning, PCR, quantitative RT-PCR, and retroviral transduction.

Preferred skills:

• Experience with bioinformatics tools for large data set analysis.
• Prior experience with tumor immunology in murine models
• Experience using Seahorse with whole cell metabolism related assays and metabolomics.
• Prior grant-writing experience and evidence of procuring any competitive funding (amount not important).